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Cell3iMager neo
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Co-Microencapsulation of Islets and MSC CellSaics, Mosaic-Like Aggregates of MSCs and Recombinant Peptide Pieces, and Therapeutic Effects of Their Subcutaneous Transplantation on Diabetes
Yusuke Mochizuki, Ryo Kogawa, Ryuta Takegami, Kentaro Nakamura, Akira Wakabayashi, Tadashi Ito and Yasuhiro Yoshioka
Biomedicines 2020, 8(9), 318; Published: 31 August 2020 -
PREDICTING METABOLISM-RELATED DRUG-DRUG INTERACTIONS USING A MULTI-TISSUE MICROPHYSIOLOGICAL SYSTEM
Christian Lohasz, Flavio Bonanini, Kasper Renggli, Olivier Frey, and Andreas Hierlemann.
ETH Zurich NO. 26595, 2020 -
High-throughput, bright-field imaging of 3D tumor spheroid growth and morphology for therapeutic and efficacy screening: A study using chemotherapeutic compounds
Leena Mol Thuruthippallil, Jens M. Kelm and David Fluri
Volume 14, Issue 12 Supplement 2, pp. B75 Published December 2015 DOI:https://doi.org/10.1158/1535-7163.TARG-15-B75 -
Issues with Cancer Spheroid Models in Therapeutic Drug Screening
Eleonore Fröhlich
Curr Pharm Des. 2020;26(18):2137-2148. doi: 10.2174/1381612826666200218094200 -
Predicting Metabolism-Related Drug–Drug Interactions Using a Microphysiological Multitissue System
Christian Lohasz,Flavio Bonanini,Lisa Hoelting,Kasper Renggli,Olivier Frey,Andreas Hierlemann
Advanced BiosystemsVolume 4, Issue 11 2000079 First published: 19 October 2020 https://doi.org/10.1002/adbi.202000079 -
Cathepsin V suppresses GATA3 protein expression in luminal A breast cancer
Naphannop Sereesongsaeng, Sara H. McDowell, James F. Burrows, Christopher J. Scott & Roberta E. Burden
Breast Cancer Research volume 22, Article number: 139 (2020) Published:09 December 2020 DOI:https://doi.org/10.1186/s13058-020-01376-6 -
SNAIL regulates gastric carcinogenesis through CCN3 and NEFL
Ru Chen, Kenji Masuo, Akitada Yogo, Shoko Yokoyama, Aiko Sugiyama, Hiroshi Seno, Akihiko Yoshizawa, Shigeo Takaishi
Carcinogenesis, Volume 42, Issue 2, February 2021, Pages 190–201, https://doi.org/10.1093/carcin/bgaa133 Published: 12 December 2020 -
HNC0014, a Multi-Targeted Small-Molecule, Inhibits Head and Neck Squamous Cell Carcinoma by Suppressing c-Met/STAT3/CD44/PD-L1 Oncoimmune Signature and Eliciting Antitumor Immune Responses
Jih-Chin Lee ,Alexander T. H. Wu ,Jia-Hong Chen ,Wen-Yen Huang ,Bashir Lawal ,Ntlotlang Mokgautsi ,Hsu-Shan Huang and Ching-Liang Ho
Cancers 2020, 12(12), 3759; https://doi.org/10.3390/cancers12123759 Published: 14 December 2020 -
PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O6-methylguanine DNA damage in glioblastoma
Shaofang Wu, Xiaolong Li, Feng Gao, John F de Groot, Dimpy Koul, W K Alfred Yung
Neuro-Oncology, Volume 23, Issue 6, June 2021, Pages 920–931, https://doi.org/10.1093/neuonc/noab003 Published: 12 January 2021 -
Regulation of carcinogenesis and mediation through Wnt/β-catenin signaling by 3,3′-diindolylmethane in an enzalutamide-resistant prostate cancer cell line
Chih-Wei Tsao, Jia-Sin Li, Ya-Wen Lin, Sheng-Tang Wu, Tai-Lung Cha & Chin-Yu Liu
Scientific Reports volume 11, Article number: 1239 (2021) Published:13 January 2021 DOI:https://doi.org/10.1038/s41598-020-80519-3 -
Cancer-Associated Fibroblast Subgroups Showing Differential Promoting Effect on HNSCC Progression
Soo Hyun Kang ,Su Young Oh ,Heon-Jin Lee ,Tae-Geon Kwon ,Jin-Wook Kim ,Sung-Tak Lee ,So-Young Choi and Su-Hyung Hong
Cancers 2021, 13(4), 654; Published: 6 February 2021 https://doi.org/10.3390/cancers13040654 -
S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
MasayasuToyomoto ,AsukaInoue ,KeiIida ,MasatsuguDenawa ,IsaoKii ,Francois MarieNgako Kadji ,TakayukiKishi ,DohyunIm ,TatsuroShimamura ,HiroshiOnogi ,SuguruYoshida ,SoIwata ,JunkenAoki ,TakamitsuHosoya ,MasatoshiHagiwara
Cell Chemical Biology Volume 28, Issue 8, 19 August 2021, Pages 1132-1144.e9 https://doi.org/10.1016/j.chembiol.2021.01.004https://doi.org/10.1016/j.chembiol.2021.01.004 -
Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for glioblastoma multiforme
Lynn N Jena, Lindsey A Bennie, Emma M McErlean, Sreekanth Pentlavalli, Kim Glass, James F Burrows, Vicky L Kett, Niamh E Buckley, Jonathan A Coulter, Nicholas J Dunne & Helen O McCarthy
Journal of Nanobiotechnology volume 19, Article number: 127 (2021) Published:04 May 2021 DOI:https://doi.org/10.1186/s12951-021-00856-x -
Expression and cell transformation activity of dynactin-associated protein isoforms
Xiaobo Yin,Shota Yamada,Hiroaki Kobayashi,Ryota Tanaka,Yuki Togo,Miho Hosoi,Mie Tsuchida,Tatsuki Kunoh,Shuichi Wada,Toshinobu Nakamura,Ryuzo Sasaki,Tamio Mizukami,Makoto Hasegawa
FEBS Open BioVolume 11, Issue 8 p. 2110-2117 First published: 27 May 2021 https://doi.org/10.1002/2211-5463.13202 -
Gene Expression Profiles Associated with Radio-Responsiveness in Locally Advanced Rectal Cancer
Jeeyong Lee ,Junhye Kwon ,DaYeon Kim ,Misun Park ,KwangSeok Kim ,InHwa Bae ,Hyunkyung Kim ,JoonSeog Kong ,Younjoo Kim ,UiSup Shin and EunJu Kim
Biology 2021, 10(6), 500; https://doi.org/10.3390/biology10060500 Published: 3 June 2021 -
Microfluidic Co-Culture Platform to Recapitulate the Maternal–Placental–Embryonic Axis
Julia A. Boos,Patrick M. Misun,Giulia Brunoldi,Lea A. Furer,Leonie Aengenheister,Mario Modena,Nassim Rousset,Tina Buerki-Thurnherr,Andreas Hierlemann
Advanced BiologyVolume 5, Issue 8 2100609 First published: 19 June 2021 https://doi.org/10.1002/adbi.202100609 -
A Patient-Derived Organoid-Based Radiosensitivity Model for the Prediction of Radiation Responses in Patients with Rectal Cancer
Misun Park ,Junhye Kwon ,Joonseog Kong ,Sun Mi Moon ,Sangsik Cho ,Ki Young Yang ,Won Il Jang ,Mi Sook Kim ,Younjoo Kim and Ui Sup Shin
Cancers 2021, 13(15), 3760; https://doi.org/10.3390/cancers13153760 Published: 27 July 2021 -
Differential Angiogenic Potential of 3-Dimension Spheroid of HNSCC Cells in Mouse Xenograft
So-Young Choi ,Soo Hyun Kang ,Su Young Oh ,Kah Young Lee ,Heon-Jin Lee ,Sangil Gum ,Tae-Geon Kwon ,Jin-Wook Kim ,Sung-Tak Lee ,Yoo Jin Hong ,Dae-Geon Kim and Su-Hyung Hong
Int. J. Mol. Sci. 2021, 22(15), 8245; https://doi.org/10.3390/ijms22158245 Published: 31 July 2021 -
Hypoxia-targeted cupric-tirapazamine liposomes potentiate radiotherapy in prostate cancer spheroids
Vera L.Silva, AmaliaRuiz ,AhlamAli ,SaraPereira ,JaniSeitsonen ,JanneRuokolainen ,FionaFurlong ,JonathanCoulter Wafa’ T.Al-Jamal
International Journal of PharmaceuticsVolume 607, 25 September 2021, 121018 doi:https://doi.org/10.1016/j.ijpharm.2021.121018 -
speedingCARs: accelerating the engineering of CAR T cells by signaling domain shuffling and single-cell sequencing
Raphaël B. Di Roberto, ProfileRocío Castellanos-Rueda, Fabrice S. Schlatter, Darya Palianina, ProfileOanh T. P. Nguyen, Edo Kapetanovic, ProfileAndreas Hierlemann, ProfileNina Khanna, ProfileSai T. Reddy
biorxiv Posted August 23, 2021. doi: https://doi.org/10.1101/2021.08.23.457342 -
Gamma-Mangostin Isolated from Garcinia mangostana Suppresses Colon Carcinogenesis and Stemness by Downregulating the GSK3β/β-Catenin/CDK6 Cancer Stem Pathway
Alexander THWu ,Yuan-ChiehYeh ,Yan-JunHuang ,NtlotlangMokgautsi ,BashirLawal ,Tse-HungHuang
Phytomedicine Available online 21 October 2021, 153797 DOI:https://doi.org/10.1016/j.phymed.2021.153797 -
Gravity-driven perfusion systems for the physiological culturing of arrays of microtissues
Lohasz, Christian
ETH Zurich published2020-06-10 DOI:https://doi.org/10.3929/ethz-b-000419480